lsphp5 settings looks normal.
is lsws version 4.2.21 ?
you can try a different version, like
#/usr/local/lsws/admin/misc/lsup.sh -f -v 4.2.19
(switch between versions: lsws web admin -> Actions -> Version Manager)
also not sure if change
PHP suEXEC: User's Home Directory Only to "Yes"
will make difference.
it looks the 1st time for me to hear about Nodeworx