why set ttl = 0 your memory usage will keep increasing, usually for APC i have something like
apc.ttl=7200
apc.user_ttl=3600
apc.gc_ttl = 600
never had any problems with Litespeed and LSPHP + APC
Of course make sure you aren't using LSPHP with phpSuExec for opcode cache use. I have a...